N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid CAS NO.29915-38-6

Suzhou yacoo science co.,LTD was founded in 2003. It is a high-tech enterprise which specializing in biomedicine, electrochemical materials, import and export business, electronic mall, Up to now，It has 10 years history on chemical sales, R & D and production operations. Company also set sales and service outlets in Shanghai, Beijing, Guangzhou, Jinan and other cities, which owning first-class marketing team and technical support personnel. Its famous brands-Yacoo were exported to Europe, America and Southeast Asian countries. In order to meet the demand of the market of High-tech industrial products which updates fast, respones service timely, requires high technical and grows rapidly , Yacoo has established 5000㎡  research and test center and 10000㎡ production base， which have passed ISO9001: 2008 quality system certification. We have rapid logistics network, high quality service to provide  more than 20000 kinds of products for China and global customer. Relying on its own synthesis of unique and rich experience in research and development, provide scientific products from grams to tons of commissioned service as well as the mass production services for customers.

TAPS  N-[ Tris ( hydroxymethyl ) methyl ] -3-aminopranesulfonic acid CAS NO 29915-38-6 99%

Quick detail:

Description:

> Formula:C₇H₁₇NO₆S

> Weight: 243.27

> MP/BP :231.0-235.0℃ (MP)

> Storage:room temperature

> HS:29221980

> Safety Description:S24/25

> Danger Description:R36/37/38

> Danger Symbol: Xi

> Shelf life: two years

1.Applications:

A.A test kit for detection of high-density lipoprotein cholesterol

B.Semiautomated pH Gradient Ion-Exchange Chromatography of Monoclonal Antibody Charge Variants

2.Location:

A.biology/biochemistry laboratory, pharmaceutical factory, cosmetics factory,dyestuff factory

Synonyms:

TAPS;TAP;N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANESULFONIC ACID;N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANE-SULPHONIC ACID;3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID;3-[[TRIS(HYDROXYMETHYL)METHYL]AMINO]PROPANESULFONIC ACID;3-[N-TRIS-(HYDROXYMETHYL)METHYLAMINO]-PROPANESULPHONIC ACID;3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid;3-[[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid; 3-[(Tris(hydroxymethyl)methyl)amino]-1-propanesulfonic acid; N-(tris(hydroxymethyl)methyl)-3-aminopropanesulfonic acid; TAPS; 3-(tris(hydroxymethyl)methylamino)propane-1-sulphonic acid; N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid; 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonic acid; 1-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonic acid; N-[tris(hydroxymethyl)methyl]-3-amionpropanesulfonic acid

Related categories:API intermediates;Biochemistry;Good's Buffers;Buffer

Related Products:1132-61-2;68399-81-5

The determination of Loss on drying

  Weigh a sample of approximately 2g (weighing accuracy 0.0001g),Record the weight of m,The sample was placed in a Petri dish constant weight (weight recorded as m0), the tile, the thickness of not more than 5mm, into the oven (As next dish cover removed) drying at 105-110 ℃ 3 hours.When removing, make sure the dish cover,be placed in a desiccator to cool, then weighed and the weight (including surface dish) m1.

Loss on drying in accordance with the following formula:

Where:

       m-- sample, g

       m0-- dish, g

       m1-- After drying the quality of the sample and the dish, g

The determination of PH

Weigh a certain amount of samples into test tube, add a certain amount of water, shake and dissolve, determination of the pH used have been calibrated pH meter.

The determination of solubility

Weigh a certain amount of samples into test tube, add a certain amount of water, shake and dissolve, observe the solution.

Detection of heavy metals

    The meaning of heavy metals of this act is under the specified experimental condition, which can coloration effects with sodium sulfide or thioacetamide  .The glasses of preparation or storage is not allowed to contain lead.

5.8.1  Reagents

  a) Lead dinitrate:1μg/mL

  b) Sodium hydroxide :10%(m/v)

  c) Sodium sulfide :10%(m/v)

5.8.2  Preparation of lead standard solution

    Weigh lead dinitrate  0.1599g ,relocated to 1000mL volumetric flask, plus nitric acid 5mL and water 50mL, diluted with water to the mark , shake, as the stock solution.

5.8.3 Determination of step

  Before use, the exact amount of stock solution 1mL, relocated to a 100ml volumetric flask, dilute with water to the mark, shake, limit the use of the day .

  Weigh sample 1g, after adding sodium hydroxide solution 5mL and 20mL of water to dissolve, set Nessler colorimetric tube, add 5 drops of sodium sulfide , shake , compared the color with 5mL lead standard solution after the sametreatment,  not deeper.

The determination of UV absorbance

A certain amount of the sample was weighed to the nearest 0.0001g, into 10ml volumetric flask, after constant volume with pure water, at a specific wavelength by 2cm cuvette was measured by UV spectrophotometer.

Determination of melting point

Instrument:

Micro melting point apparatus WRS-2A, Melting point tubes

Determination of step:

Open switch, stable 20min.

First set the starting temperature than the melting point of the low 10 ℃, heating rate 2 ℃ / min.

The sample was grind as fine as possible and load in a clean, dry melting point pipe ,until the sample was compressed into about 1cm high .When the actual temperature reaches the set temperature and stabilized . Inserted into the capillary with the sample, the simultaneous determination of three.